Clinical evidence

Clinical studies keep generating a series of intriguing data with significant impact on current understanding and practice of implant therapy.


A 2.5 year-follow-up study analyzed 95 consecutive patients who received untreated implants and 70 patients who received photofunctionalized implants. The healing time before functional loading was substantially decreased in patients who received photofunctionalized implants (less than half period of time) compared with that in patients who received untreated implants. Despite this substantially shortened protocol, the success rate of photofunctionalized implants was as high as untreated implants. The ISQ increase per month for photofunctionalized implants was considerably higher than that of as-received surfaces reported in the literature. The average length and diameter for photofunctionalized implants were significantly smaller than those for untreated implants.


A case series comprehensively evaluated photofunctionalized implants placed into complex cases of either fresh extraction socket, vertically augmented bone, simultaneous sinus-lifted site, or site of a failing implant. At a 1-year follow-up, all implants remained functional and healthy, despite a substantially earlier loading protocol applied than reported for similar cases. The success rate was 100%. Implant stability evaluation by ISQ values demonstrated a considerably accelerated rate of increase per month compared to the reported numbers of ISQ in literature. Unlike the common understanding that a certain degree of marginal bone loss is unavoidable, the average marginal bone level significantly increased at the 1-year follow-up; the bone level progressed coronally in some cases even exceeding the platform level.


A cohort design was employed to evaluate implants placed in the maxilla and immediate loaded. The rate of establishing implant stability substantially increased in photofunctionalized implants when their initial stability was low. When their initial stability was high, the ISQ was maintained at a high value, eliminating any stability dip. In both cases, the degree of implant stability achieved by photofunctionalization was considerably higher than reported data in literature. 

Copyright(c) APIB All Rights Reserved.